Daijiworld Media Network – New York
New York, Dec 2: New research highlights that dementia risk goes beyond memory loss and age, identifying high “bad” cholesterol (LDL) in midlife and untreated vision loss in later years as significant, preventable factors. The Lancet Commission on dementia prevention reports that these two factors together account for around 9% of global dementia cases, with 7% linked to high LDL cholesterol and 2% to untreated vision loss.
Dementia, a progressive brain disorder affecting cognition, mood, and personality, currently impacts over 55 million people worldwide, with nearly 10 million new cases each year. Experts warn the number of cases could triple by 2050 if preventive measures are not adopted.

High LDL cholesterol in midlife may contribute to brain damage through vascular harm and protein buildup, making early intervention through diet, exercise, and medication crucial. Untreated vision loss reduces mental engagement and social interaction, accelerating cognitive decline, which can often be prevented with timely eye care such as glasses or cataract treatment.
Early warning signs extend beyond memory loss and include declining focus, difficulty navigating familiar places, social withdrawal, mood changes, and slower decision-making. Experts emphasize that identifying and managing these risks early can significantly reduce dementia chances.
Preventive steps include monitoring cholesterol, scheduling regular eye exams, staying physically and socially active, and maintaining a heart-healthy, brain-friendly lifestyle. This research underscores that dementia is not an inevitable fate, and timely action can protect both brain and overall health.