Lab-generated stem cells set for human trial in Japan


Tokyo, Sep 11 (IANS): In a major boost to stem cell research, a Japanese patient with a debilitating eye disease is set to become the first person in the world to be treated with induced pluripotent stem (iPS) cells.

A 19-member health ministry committee here vetted the researchers' safety tests and cleared the team to begin the experimental procedure, the scientific journal Nature reported.

Masayo Takahashi, an ophthalmologist at the RIKEN Center for Developmental Biology (CDB) in Kobe has been using induced pluripotent stem (iPS) cells to prepare a treatment for age related macular degeneration.

The Japanese team will now use iPS cells to treat the patient with degenerative eye disease.

During her research on mice and monkeys, Takahashi took skin cells from people with the disease and converted them to iPS cells.

She then coaxed these cells to become retinal pigment epithelium cells and then to grow into thin sheets that can be transplanted onto the damaged retina.

In monkey studies, iPS cells generated from the recipients' own cells did not provoke an immune reaction that caused them to be rejected.

They are capable of becoming any cell type in the body and have the potential to treat a wide range of diseases.

The news could be a welcome boost for the CDB which has been mired in controversy over studies on stem cell research that were later retracted, the Nature report added.

 

  

Top Stories


Leave a Comment

Title: Lab-generated stem cells set for human trial in Japan



You have 2000 characters left.

Disclaimer:

Please write your correct name and email address. Kindly do not post any personal, abusive, defamatory, infringing, obscene, indecent, discriminatory or unlawful or similar comments. Daijiworld.com will not be responsible for any defamatory message posted under this article.

Please note that sending false messages to insult, defame, intimidate, mislead or deceive people or to intentionally cause public disorder is punishable under law. It is obligatory on Daijiworld to provide the IP address and other details of senders of such comments, to the authority concerned upon request.

Hence, sending offensive comments using daijiworld will be purely at your own risk, and in no way will Daijiworld.com be held responsible.