Daijiworld Media Network – New Delhi

New Delhi, Apr 3: A new study published in the March 2026 issue of JNCCN—Journal of the National Comprehensive Cancer Network suggests that simple exercise routines can help cancer patients stay mentally sharp and better manage daily activities during chemotherapy.

The nationwide Phase III trial, conducted across the United States, found that patients who followed a structured exercise programme alongside chemotherapy experienced significantly less cognitive decline compared to those who did not. The programme, known as EXCAP, included personalised walking routines and resistance band exercises.

The study, involving 687 patients from 20 oncology centres under the University of Rochester Cancer Center, revealed that benefits were most notable among patients undergoing chemotherapy in two-week cycles. These participants reported reduced mental fatigue and better cognitive function, while also maintaining their daily physical activity levels.

Lead researcher Karen M. Mustian said that such simple and safe exercise routines could play a vital role in supportive cancer care. “Cancer care providers should consider incorporating structured, home-based exercise prescriptions into routine chemotherapy care,” she noted.

Co-author Po-Ju Lin highlighted that patients without an exercise plan often reduced their daily walking by nearly half and experienced increased memory and concentration issues.

Experts say the findings offer hope to patients concerned about “chemo brain,” a common side effect involving cognitive impairment during treatment. Independent expert Lindsay L. Peterson said the study reinforces the importance of physical activity in maintaining mental resilience and quality of life during cancer treatment.

Researchers added that exercise-based interventions are safe, cost-effective, and can be performed at home, making them a practical option for improving patient outcomes during chemotherapy.